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Objective:To explore the effects of game addiction disorders on brain cognitive control functions based on near-infrared spectroscopy.Methods:Thirteen subjects were screened according to the Online Game Addiction (OGA) Scale. The experimental paradigm was the stop-signal task. The relative concentration levels of oxyhemoglobin (HbO 2) and deoxyhemoglobin (Hb) in the prefrontal region of the brain during cognitive activity were collected using near-infrared spectroscopy to assess the cognitive control function of the subjects. Results:The game-addicted patients had lower keystroke accuracy in the stop-signal task than healthy subjects, and the difference was statistically significant ( P<0.05). Compared to healthy subjects, game-addicted patients had less activation in prefrontal areas and showed uncontrolled behavior and brain activity. Conclusions:Game addiction disorders impair brain cognitive control, which in turn triggers a weakening of cognitive control. The results of this study provide a reference for the prevention and treatment of game addiction.
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Introducción: La relación entre el TDAH y la epilepsia, aunque muy frecuente, no es clara. Los estudios clínicos en neuropsicología y neurología (neuropsiquiatría) pueden ofrecer información valiosa para la evaluación, la intervención y el tratamiento. Método: Se realizó un estudio con diseño no experimental, enfoque cuantitativo, nivel descriptivo y corte transversal con el objetivo de comparar el funcionamiento ejecutivo de un grupo de niños con TDAH y un grupo de niños con TDHA y EBPCT. Se conformó una muestra por conveniencia de 40 niños emparejados (todos hombres) agrupados en dos grupos de 20 con edades entre los 7 y los 13 años. Para realizar la evaluación del funcionamiento ejecutivo se aplicaron algunas pruebas de la Batería Neuropsicológica de Funciones Ejecutivas y Lóbulos Frontales - BANFE. Resultados: De acuerdo con los valores de la significancia asintótica bilateral, se encontraron diferencias estadísticamente significativas en las variables Stroop A - Aciertos, Stroop B - Aciertos, Señalamiento autodirigido (Aciertos, Planeación y Tiempo), y Memoria de Trabajo Visoespacial (Nivel máximo, Perseveraciones y Errores de orden). Conclusiones: Los resultados del presente estudio coinciden con los fallos en el control inhibitorio y los problemas de atención sostenida reportados en la literatura. Los niños con EBPCT y TDAH tienen un perfil de funcionamiento ejecutivo diferente y más deteriorado que los niños con TDAH solo.
Introduction: The relationship between ADHD and epilepsy, although very frequent, is not clear. Clinical studies in neuropsychology and neurology (neuropsychiatry) can provide valuable information for assessment, intervention and treatment. Method: A non-experimental design, quantitative approach, descriptive level and cross-sectional study was carried out with the aim of comparing the executive functioning of a group of children with ADHD and a group of children with ADHD and CPSDD. A convenience sample of 40 matched children (all males) grouped in two groups of 20 children between 7 and 13 years of age was formed. In order to evaluate executive functioning, some tests of the Neuropsychological Battery of Executive Functions and Frontal Lobes - BANFE were applied. Results: According to the bilateral asymptotic significance values, statistically significant differences were found in the variables Stroop A - Hits, Stroop B - Hits, Self-directed Signaling (Hits, Planning and Time), and Visuospatial Working Memory (Maximum Level, Perseverations and Order Errors). Conclusions: The results of the present study coincide with the failures in inhibitory control and sustained attention problems reported in the literature. Children with EBPCT and ADHD have a different and more impaired executive functioning profile than children with ADHD alone.
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Congenital lobar emphysema (CLE), also known as congenital alveolar overdistension, is a developmental anomaly of the lower respiratory tract that is characterized by hyperinflation of one or more of the pulmonary lobes. CLE is a rare congenital malformation with a prevalence of 1 in 20,000 to 1 in 30,000. We are reporting a 4-month-old boy presented with complaints of cough and cold for 3 days with history of similar complaints in the past at age of 1month and 2 months. Investigations revealed hyperlucency of left upper zone with tracheal shift and mild shift of the heart to the right. Elective Left Upper Lung Lobectomy was done and Appropriate supportive therapy given and child recovered well.
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Few reports have been published regarding the use of ultrasonography as a method of evaluating the normal thyroid gland in horses. For these reasons, this study aimed at determining reliably of the thyroid measurements from the comparison between the left and right thyroid lobes, as well as assessing the contour, format, echotexture and echogenicity of the healthy thyroid by mode-B ultrasonography. Additionally, the equine thyroid vascularization was quali-quantitatively characterized the by Doppler. The sample size initially was determined by the animal selection with advanced age and without volume increase in the neck proximal region. Finally, eleven horses were selected by laboratory test, search of thyroid neoformations by ultrasonography and cytology thyroid. Next, these animals were submitted to thyroid lobes ultrasonographic evaluation. Excellent reproducibility was observed for all measurements obtained. Among the comparisons made between the quantitative parameters of the left and right lobes, it was observed that there was only difference between their respective lengths. Qualitatively, there was a significant variation between the lobes elliptical format in the longitudinal plane of some glands, which oscillated between a rounded and flattened conformation. Thus, we can conclude that the difference between the lobes format of some thyroids can be explained by the significant difference observed between the length of the left and right lobes. Additionally, it was verified that there was no difference between the Doppler quantitative parameters. Therefore, we may suggest that unilateral analysis of the cranial thyroid artery by spectral Doppler can be used to evaluate equine thyroid diffuse disorders.(AU)
Poucas análises foram publicadas com relação ao uso da ultrassonografia como método de avaliação da glândula tireoide hígida em equinos. Alguns trabalhos incluem a determinação das dimensões e características do parênquima. Por essas razões, este estudo teve como objetivo determinar com segurança as medidas tireoidianas a partir da comparação entre o lobo tireoidiano esquerdo e direito, bem como avaliar os contornos, formato, ecotextura e ecogenicidade das glândulas tireoides hígidas pela ultrassonografia em modo B. Além disso, a vascularização da tireoide equina foi caracterizada quali-quantitativamente pela ferramenta Doppler. O tamanho da amostra inicialmente foi determinado pela seleção dos animais com idade avançada e sem aumento de volume na região proximal do pescoço. Por fim, onze equinos foram selecionados por meio de exame laboratorial, pesquisa de neoformações tireoidianas por ultrassonografia e citologia da tireoide. Em seguida, estes animais foram submetidos à avaliação de lobos tireoidianos por ultrassonografia. Observou-se excelente reprodutibilidade em relação a todas as medidas deste estudo. Foram observadas diferenças qualitativas entre os lobos tireoidianos direito e esquerdo. Assim, podemos concluir que tais diferenças entre o formato dos lobos tireoidianos podem ser explicadas pela diferença significativa e/ou tendência observada no parâmetro comprimento entre os respectivos lobos. Além disso, não foi encontrada diferença significativa entre os valores da artéria tireoidiana cranial esquerda em relação aos obtidos na artéria tireoidiana cranial direita, sugerindo que a análise dos valores espectrais do Doppler de uma das artérias tireoidianas craniais possa ser utilizada como método de avaliação de distúrbios difusos da tireoide equina.(AU)
Subject(s)
Animals , Thyroid Gland/anatomy & histology , Thyroid Gland/diagnostic imaging , Horses , Ultrasonography/veterinaryABSTRACT
Modelo do estudo: Relato de caso. Importância do problema: Lobos e fissuras acessórias nos pulmões podem induzir a erros de interpretação e diagnóstico, além de favorecer a disseminação de patologias como a pneumonia para lobos adjacentes. Dessa forma, a constatação dessas alterações anatômicas pode colaborar em diagnósticos clínicos e procedimentos cirúrgicos. Comentários: Relatamos um caso raro de modificação anatômica nos lobos e fis-suras dos pulmões. O pulmão esquerdo exibia um lobo médio acessório e uma fissura horizontal completa. Por outro lado, o pulmão direito apresentava duas fissuras acessórias incompletas situadas inferiormente na face costal do lobo médio. Além disso, observamos que o hilo do pulmão esquerdo continha dois brônquios lobares (superior e inferior), um brônquio lobar acessório e três artérias pulmonares. O conhecimento das variações anatômicas aqui relatadas é fundamental, pois auxiliam os profissionais da saúde nos diagnósticos e nas decisões terapêuticas e cirúrgicas.(AU)
Study: Case Report. Importance: Lobos and accessory fissures in the lungs can induce errors of interpretation and diagnosis, as well as favor the spread of pathologies such as pneumonia to adjacent lobes. Thus, the confirmation of these anatomical alterations can collaborate in clinical diagnoses and surgical procedures. Comments: We report a rare case of anatomical variation in the lobes and fissures of the lungs. The left lung showed an accessory middle lobe and a complete horizontal fissure. On the other hand, the right lung had two incomplete accessory fissures located inferiorly in the costal face of the middle lobe. In addition, we observed that the left lung hilum contained two lobar bronchi (upper and lower), one accessory lobar bronchus and three pulmonary arteries. Knowledge of the anatomical variations reported here is fundamental, as they help health professionals in diagnoses and therapeutic and surgical decisions (AU)
Subject(s)
Humans , Male , Cadaver , Anatomic Variation , Lung/anatomy & histologyABSTRACT
Background and aims: Knowledge of anatomical variations in lung morphology is not only of academic interestbut is essential during surgery and also while interpreting various radiological images. The present study wasundertaken with the aim to observe the variations of lung morphology.Materials and Methods: The shape of the lungs, variations of fissures, lobes and hilar structures were studied in42 right and 37 left isolated lungs.Results: Unusual shape was seen in 4 lungs. Among the right lungs, oblique fissure was incomplete in 42.86% andabsent in 7.14% and horizontal fissure was incomplete in 61.90% and absent in 19.05%. Inferior accessoryfissure (IAF) was present in 21.43% and superior accessory fissure (SAF) in 7.14%. Usual right hilar architecturehaving a pulmonary artery with 2 pulmonary veins and 2 bronchi was not seen in any case however, the usualarchitecture with a superior lobar artery was seen in 28.57% cases. Among the left lungs, oblique fissure wasincomplete in 40.54% and absent in 2.70%. Horizontal fissure was present in 24.32%, left minor fissure (LMF) in29.73%, inferior accessory fissure (IAF) in 43.24% and superior accessory fissure (SAF) in 2.70%. Usual left hilararchitecture having a pulmonary artery, 2 pulmonary veins and a bronchus was seen in 54.06%.Conclusion: The knowledge of variations in the lung morphology observed in this study will be of academicinterest and also useful for diagnostic and clinical management of pulmonary and even cardiac cases
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Introduction: Liver is the largest gland of the body. Itis situatedunder the right dome of the diaphragm andmainlyoccupies the right hypochondriac and epigastricregions. In man, the liver is essentialfor survival since there iscurrently no artificial organ orequipment that has the capacityto compensate for theabsence of liver function. Henceknowledge of variation in liver anatomy is required for goodsurgical outcome, diagnostic imaging and minimally invasivesurgical procedures.Material and Methods: The present study was conducted in160 human livers from embalmed cadavers in the Departmentof Anatomy, KIMS, Karad, during the study duration of July2017 to August 2018. The liver specimens were removed fromadult human cadavers during routine dissection for medicalundergraduate students and then preserved in 10% of formalin.Results: We analyzed 160 livers, with its morphologicalcharacteristics and structural variations. Mean weight ofthe liver was reported to be 1.05 Kg (Minimum 0.461 andMaximum 2.137 Kg) with SD of 0.34 Kg. Mean breadth ofliver was reported to be 18.44 cm (Maximum 25.5 cm andMinimum 2.4 cm) with SD of 2.45 cm. Mean thickness of liverwas reported to be 10.52cm (Maximum 18.3 and Minimum3.4) with SD of 1.82 cm.Conclusion: The present study focuses upon the frequentoccurrence of morphological variations on the surface of theliver.
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Introduction: Awareness of anatomical variations in lungs is essential during segmental or lobar resections oflungs. Hence the proposed aim of the study was to study the fissures and lobes of the lungs and their variationsand to compare them with previous studies and to find their clinical implications.Materials and Method: Seventy lungs obtained from cadavers in the department of anatomy, Govt DharmapuriMedical College were used for study. Any variation in the fissures and lobes of the lungs and accessory fissurewere studied.Result: Out of seventy lungs studied, 32 were from right side and 38 were from left side. Out of 32 right lungsexamined, the horizontal fissure was absent in 4 lungs (12.5%), incomplete in 10 lungs (31.25%), Complete in 18lungs (56.25%). Oblique fissure was incomplete in 5 lungs (16%) and complete in 27 lungs (84%). Out of 38 leftlungs, the oblique fissure was incomplete in 8 lungs (21%), complete in 30 lungs (79%) and accessory fissure in5 lungs.Conclusion: Knowledge of such variations will be helpful to the radiologists, clinicians to make correct diagnosisand plan for the surgical procedure. This will help to reduce the morbidity and mortality associated with lungsurgeries.
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Introduction: Lungs are the paired vital organs meant for respiration situated in the thoracic cavity on either sideof the heart. The right lung is divided into supe-rior, middle & inferior lobes by oblique and horizontal fissure.While the left lung is divided into supe-rior & inferior lobes by an oblique fissure. The fissures permit distensionof the lobes during respiration. The fissures may be complete, incomplete or absent.Aim: To find out the variations in fissures and lobes along with their patterns, in human lungs; collected fromcadavers.Result: Out of 50 right lung specimen, the horizontal fissure was absent in two cases whereas the horizontalfissure was incompletely seen in 18 specimens. Incomplete oblique fissure was seen in 7 right sided lungs. Wereported accessory fissures and accessory lobes in 14 specimens. The oblique fissure was absent in 4 left lungsand it was incomplete in 14 lungs. Accessory fissures and lobes were present in 8 specimens.Conclusion: Knowledge of any variations is necessary in performing segmental resection and lobectomy. Accessoryfissures indicate persistence of prenatal fissures.
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Background: The lungs are the essential organs of respiration which are divided into lobes and fissures. Fissureshelp in a more uniform expansion of lungs. Knowledge about the fissures is helpful in appreciation of lobaranatomy and for locating bronchopulmonary segments and it is important for anatomists, pediatrician,radiologists, cardiothoracic surgeons and also for clinicians.Materials and methods: 50 spontaneously aborted fetuses were collected from labour room of Obstretrics andGynaecology Department of PSG Institute of Medical Science and Research Centre, Coimbatore and the study wasconducted in the Department of Anatomy. The morphological details of fissures and lobes of the lungs andpresence of any variation in the fissures and accessory fissure were studied.Results: Out of 50 specimens in the age group of 10 weeks to 39 weeks of gestation, the horizontal fissure wasincomplete in 35 fetuses (68%), complete in 14 fetuses (28%), absent in 1 fetus (2%) and accessory fissure wasfound in 1 fetus (2%).Conclusion: Awareness of the variations in the lobes and fissures of the lungs is important for radiologists forproper diagnosis and to surgeons for performing segmental lung resections.
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The fissures of lungs are embryologically separating the bronchopulmonary segments, which later on persist in interlobar planes of fully developed lung. Fifty lungs (23 right side and 27 left side), obtained during routine dissection and preserved in formalin constituted the material for present study. In them, variations in fissures and lobes of lung were observed and compared with the previous studies. Seven right sided and 14 left sided lungs showed incomplete oblique fissure. Incomplete horizontal fissure of right lung was observed in eight lungs while it was completely missing in three specimens. A right lung with “lobe of the azygos vein” separated by a supernumerary fissure in medial surface was found. One of the right lung had both superior accessory fissure and inferior accessory fissure and four other right lungs and one left lung presented only with inferior accessory fissure. A vertical notch was found in middle lobe of one right lung. Eight left lungs exhibited with left minor fissure among them two lungs had lingula appearing as a separate lobe. Knowledge of variations in fissures and lobes is of interest to all medical professionals to exactly interpret radiographs, computed tomography scans, to diagnose, plan and modify a surgical procedure depending on the merit of the case and also in certain classical clinical cases pertaining to lung pathologies.
Subject(s)
Humans , Cadaver , Formaldehyde , Lung , PathologyABSTRACT
Anatomical variations of lungs in the form of Accessory lobe and abnormality in the fissures are important for the surgeons to avoid possible injuries to the neighbouring structures. We report a case of Accessory lobe of right lung between middle and lower lobe in a male cadaver which was found during routine dissection in the Anatomy department, PSG IMS & R. Fissure and lobes of left lung was normal. Anatomical knowledge of such variations are helpful for Cardiothoracic surgeons in lobectomies, surgical resections involving individual segments and for Radiologists for interpreting X – rays,CT & MRI scans.
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Objective To study the clinical therapeutic effect of combination of Naodekang capsule and western medicine for treatment of patients with mental disorders after bilateral cerebral frontal lobes contusion and laceration.Methods A prospective study was conducted. Sixty-two patients with mental disorders after bilateral frontal lobes contusion and laceration hospitalized from June 2012 to January 2014 in the Department of Neurosurgery in Liangzhou Hospital, Wuwei City, Gansu Province were enrolled. According to random principle, they were divided into combined traditional Chinese and western medicine treatment group (32 cases) and western medicine treatment control group (30 cases). Conventional symptomatic therapy was given to both groups. In the western medicine control group, based on the above conventional treatment, antipsychotic drug risperdal (risperidone) was given, the beginning dosage was 4 mg daily and gradually reduced to 1 mg daily. In combined traditional Chinese and western medicine group, beside the conventional therapy, oral Naodekang capsules and oral risperdal were given. The ingredients of the capsule included: Astragalus 60 g, Radix Paeoniae Rubra 15 g, Rhizoma Chuanxiong 25 g, Angelica 15 g, Earthworm 10 g, Semen Persicae 10 g, Safflower 15 g, Salvia miltiorrhiza 15 g, Rhizoma Gastrodiae 15 g, Uncaria 10 g, Bupleurum 20 g, Pueraria 15 g, Rhizoma Acori Tatarinowii 15 g; the patients took once 3 capsules, three times a day, and risperdal 2 mg per day at the beginning and gradually reduced to 1 mg daily. Before treatment and after treatment for 2, 6 and 12 weeks, the brief psychiatric rating scale (BPRS) score was applied to evaluate the clinical therapeutic effect on the situation of patients' improvement of symptoms; in the two groups, the clinical curative effects were observed and when the psychiatric symptoms were controlled, the mean dosage of antipsychotic western medicine used daily in each patient was calculated.Results After treatment, the BPRS scores in the two groups were lower than those before treatment, from 6 weeks after treatment, the degree of descent in the BPRS score in the combined treatment group was more significant than that in the western medicine group (38.68±7.81 vs. 54.05±6.75,P < 0.05), and the descent was persistent until 12 weeks after treatment (15.46±8.51 vs. 23.98±8.03,P < 0.05). The cure rate of the combined group was markedly higher than that in western medicine group [84.4% (27/32) vs. 76.6% (23/30),P < 0.05]. When the psychiatric symptoms were controlled, the dosage of antipsychotic western drug used in each patient in the combined group was less than that in western medicine group (mg/d: 1.5±0.1 vs. 2.8±0.2,P < 0.05).Conclusion The westernconventional therapy combined with traditional Chinese medicine Naodekang capsule for treatment of mental disorders after bilateral cerebral frontal lobes contusion and laceration has relatively good therapeutic effect.
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The liver can present a number of congenital anomalies. Most common among them are the irregularities in shape and the number of lobules. Less common variations include presence of accessory lobes or accessory fissures. The accessory lobe may be attached to the liver through a mesentery or a bridge of hepatic tissue and they are usually asymptomatic. An accessory liver lobe though a very rare occurrence but when it exists it becomes clinically important because of its rarity. We are reporting one such case of accessory caudate lobe of liver found during routine dissection of embalmed cadaver of a 60 year old male. It was separated from the caudate lobe by a well-defined fissure. The quadrate lobe and fissure for ligamentum teres were totally absent. Ligamentum teres was found embedded in the substance of the liver on its inferior surface. The presence of additional lobes and fissures or the absence of normal lobes and fissures might lead to confusion during surgery or clinical misdiagnosis. Knowledge and awareness of these anomalies is useful to the clinician to rule out diseases, surgeons during segmental resection of liver and radiologist when interpreting liver radiologic findings.
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The authors presented a historical review on Professor MacDonald Critchley, 15 years after his death.
Os autores apresentaram uma revisão histórica sobre o professor MacDonald Critchley, no seu 15º ano de falecimento.
Subject(s)
History, 20th Century , Neurology/history , EnglandABSTRACT
The Heteroptera are known for their odour, for being pests or for being disease carriers. However, they are still not extensively studied, perhaps because they form a very large group. Therefore, with the aim of enhancing the knowledge of the morphology of the testes of this insect order, we collected and analysed 18 species of terrestrial Heteroptera from the northwestern part of São Paulo. The analysis of these species revealed some differences between the testicles of these species, including their shape (elongated, oval, round or pecten), the morphology of the testicular lobes (elongated and paired side by side or united in a single region), the colours of the peritoneal sheath that surrounds the lobes (red, orange, yellow or translucent), and the number of testicular lobes (one, two, four, five, six or seven). Because the aspects analysed were highly variable, our study suggests a need for further analysis of Heteropteran testicular morphological differences.
Os Heteroptera são organismos conhecidos pelo seu odor, por serem pragas ou por serem transmissores de doenças, contudo, eles ainda são pouco estudados, talvez por formarem um grupo muito grande. Portanto, com o objetivo de ampliarmos as informações dos aspectos testiculares deste grupo analisamos 18 espécies de Heteroptera terrestres pertencentes a oito famílias que foram coletadas no Noroeste Paulista. Através das análises dessas espécies foi observado diferenças testiculares quanto: a sua forma (alongadas; ovalados; forma de concha, denominada pecten; ou arredondados); a morfologia dos lobos (alongados e pareados lado a lado ou unidos em uma única região, na forma de um “ofiuroide”); às cores da bainha peritoneal (alaranjada, amarelada, avermelhada ou transparente); ao número de lobos testiculares (um, dois, quatro, cinco, seis, sete). Devido aos aspectos analisados serem muito variáveis, nosso estudo sugere um aprofundamento maior na questão que envolve as diferenças morfológicas testiculares.
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Una forma de entender la estructura de las Funciones Ejecutivas (FE), es su estudio en el desarrollo temprano y el uso de métodos estadísticos avanzados que permiten entender la interrelación de los distintos componentes. Los hallazgos en la etapa adulta, apoyan la idea multifactorial de componentes relacionados, pero separables; mientras que evidencias recientes, en la etapa preescolar sugieren que la estructura de las FE, puede ser descrita por un solo factor. La estructura de las FE fue examinada en 128 niños de 3 a 6 años de edad, usando un análisis factorial confirmatorio. Los preescolares completaron una batería de tareas de FE, que evaluaban procesos de inhibición y memoria de trabajo, con sensibilidad adecuada para la edad. En la edad preescolar la estructura del funcionamiento ejecutivo puede ser diferenciada en dos procesos relacionados pero independientes: memoria de trabajo e inhibición. Las relaciones entre los componentes parecen cambiar en el desarrollo. La unidad estructural de las FE en edades muy tempranas, cambia a través del desarrollo, siendo cada vez más multifacética, que se relaciona con la maduración e integración de diferentes circuitos frontosubcorticales.
One way to understand the structure of executive functions (EF) is their study in early development and use of advanced statistical methods that allow us to understand the interrelationship of various components. The findings in the adult age, support the idea multifactorial of related components, but separable, while recent evidence in the preschool years suggest that the structure of the FE, can be described by a single factor. The structure of the EF was examined in 128 children aged 3 to 6 years of age, using a confirmatory factor analysis. Preschoolers completed a battery of EF tasks, assessing processes of inhibition and working memory with age-appropriate sensitivity. In the preschool the structure of executive functioning can be differentiated into two related but independent processes: working memory and inhibition. The relationships between the components seem to change in development. The structural unit of the FE at very early ages, it changes through the development, becoming more multifaceted, which is associated with the maturation and integration of different frontal-subcortical circuits.
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Una persona transexual se define como aquella que presenta una incongruencia entre el fenotipo físico y la identidad de género. Existen transexuales nacidos hombres pero con identidad de género de mujer. Se ha propuesto que uno de los orígenes de esta condición radica en los efectos que las hormonas esteroides sexuales tienen sobre el desarrollo cerebral a nivel prenatal y es posible que afecten las funciones cognitivas como las funciones ejecutivas. El objetivo fue evaluar funciones ejecutivas en transexuales hombre a mujer. Con la batería de lóbulos Frontales y Funciones Ejecutivas, se encontró que las Transexuales tuvieron una menor ejecución comparadas con los hombres en los puntajes totales de funciones ejecutivas y en los totales de corteza prefrontal orbitomedial. En las subpruebas de inhibición (Stroop) y Toma de decisiones (Juego de cartas del IOWA) las transexuales obtuvieron menores puntajes que los hombres y las mujeres. Estos resultados apoyan las evidencias que indican que las TH-M presentan una ejecución cognitiva lejana a su sexo de nacimiento y se propone un perfil cognitivo en las TH-M diferente al de los hombres y las mujeres.
Transsexualism is characterized by the development of a gender identity that is at variance with morphology of genitals and secondary sex characteristics. The origin of the transsexualism is not very clear, although some biological indicators as the prenatal androgenization seems to be one of the causes that predispose to the development of the sexual identity, as well as the cerebral anatomical differences between transsexuals and non transsexuals. Mental functions including executive functions are susceptible to be affected by sexual steroids hormones during development. The aim was to evaluate the cognitive profile in male to female transsexuals (M-FT) in absence of hormonal treatment with estrogens. With the battery of Frontal lobes and Executive Functions, transsexuals had a smaller execution compared with the men in the totals of executive functions and the totals of orbitomedial prefrontal cortex. In the sub-tests of inhibition (Stroop) and Decision making (letter Game of the IOWA) group transsexual had minor's scores than men and women. These results support the evidences that they indicate that the transsexuals display a distant mental execution to their sex of birth. We propose a cognitive profile in our transsexual group different from men and the women sets out.
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Several factors (the lengthening of the average and, to a lesser extent, of the maximum human life span; the increase in percentage of elderly in the population and in the proportion of the national expenditure utilized by the elderly) have stimulated and continue to expand the study of aging. Recently, the view of aging as an extremely complex multifactorial process has replaced the earlier search for a distinct cause such as a single gene or the decline of a key body system. This mini review keeps in mind the multiplicity of mechanisms regulating aging; examines them at the molecular, cellular, and systemic levels; and explores the possibility of interactions at these three levels. The heterogeneity of the aging phenotype among individuals of the same species and differences in longevity among species underline the contribution of both genetic and environmental factors in shaping the life span. In this mini review, several theories are identified only briefly; a few (evolutionary, gene regulation, cellular senescence, free radical, and neuro-endocrineimmuno theories) are discussed in more detail, at molecular, cellular, and systemic levels.
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La rata de laboratorio (Rattus norvegicus albinus) ha sido usada como modelo para investigaciones médicas, biológicas y moleculares, desde hace mucho tiempo. Es interesante el hecho de que no existen descripciones detalladas de la anatomía del hígado y sus ligamentos que lo fijan a la pared. El objetivo de este trabajo es definir en forma clara y acorde a los principios de la Nomina Anatomica Veterinaria el hígado y sus medios de unión en esta especie de mamífero de laboratorio. Se utilizaron 88 ratas (Rattus norvegicus albinus) de entre 250 y 450 gramos. Fueron disecadas en fresco luego de ser eutanasiadas por sobredosis de tiopental sódico intraperitoneal. Se realizó una incisión paramediana que se extendía desde el cartílago xifoides del esternón hasta el pubis y otra sobre cada arco costal hacia dorsal. Se observó que presentaba 6 lóbulos bien definidos y no presentaba vesícula biliar. Sus medios de unión eran similares a los descritos para el perro a excepción de la presencia del ligamento hepatoomental.
The laboratory rat (Rattus norvegicus albinus) has long been used as a model for medical, biological and molecular research. It is interesting that there are no detailed descriptions of the gross anatomy of the liver and ligaments that attach it to the abdominal wall. The aim of this study is to define clearly and according to the principles of the Nomina Anatomica Veterinaria, the liver and the form of attachment in this species of laboratory mammal. Eighty eight rats (Rattus novergicus albinus) were used with a weight between 250 and 450 grams. They were freshly dissected after being euthanized by an overdose of thiopental sodium given intraperitoneally. An incision from the xiphoid cartilage up to the pubic region was made and another on each costal arch toward the dorsal. Six well defined lobes were observed; gallbladder was not present. Forms of attachment were similar to those described for the dog except for the presence of the hepatoomental ligament.